polysorbate 60 kolliphor ps 60  (BASF)

Journal: Pharmaceutics

Article Title: Investigations on Alkanediols as Alternative Preservatives in a Nonionic Hydrophilic Cream

doi: 10.3390/pharmaceutics12111117

Figure Lengend Snippet: Model structure of the nonionic hydrophilic cream (NHC) according to the German Pharmacopeia (DAB) modified according to Junginger : (A) mixed crystal of polysorbate 60 and cetolstearyl alcohol, (B) interlamellarly fixed water, (C) lipophilic gel phase, (D) bulk water, (E) lipophilic dispersed phase.

Article Snippet: 1,2-Pentanediol, 2-methyl-2,4-pentanediol, and 1,2-hexanediol (Sigma-Aldrich Chemie GmbH, Taufkirchen, Germany), polysorbate 60 (Kolliphor PS 60, BASF SE, Ludwigshafen, Germany), cetostearyl alcohol (Kolliwax CSA, BASF SE, Ludwigshafen, Germany), glycerol 85% (Dr. Willmar Schwabe GmbH & Co. KG, Karlsruhe, Germany), white soft paraffin (Sasol Performance Chemicals, Hamburg, Germany), potassium sorbate (Caesar & Loretz GmbH, Hilden, Germany), citric acid (Jungbunzlauer Suisse AG, Basel, Switzerland).

Techniques: Modification

Journal: Pharmaceutics

Article Title: Investigations on Alkanediols as Alternative Preservatives in a Nonionic Hydrophilic Cream

doi: 10.3390/pharmaceutics12111117

Figure Lengend Snippet: DSC thermograms of (1) 1,2-octanediol; (2) polysorbate 60; (3) cetostearyl alcohol; (4) mixed crystal: 1,2-octanediol, standard concentration; (5) mixed crystal: 1,2-octanediol, 10-fold concentration.

Article Snippet: 1,2-Pentanediol, 2-methyl-2,4-pentanediol, and 1,2-hexanediol (Sigma-Aldrich Chemie GmbH, Taufkirchen, Germany), polysorbate 60 (Kolliphor PS 60, BASF SE, Ludwigshafen, Germany), cetostearyl alcohol (Kolliwax CSA, BASF SE, Ludwigshafen, Germany), glycerol 85% (Dr. Willmar Schwabe GmbH & Co. KG, Karlsruhe, Germany), white soft paraffin (Sasol Performance Chemicals, Hamburg, Germany), potassium sorbate (Caesar & Loretz GmbH, Hilden, Germany), citric acid (Jungbunzlauer Suisse AG, Basel, Switzerland).

Techniques: Concentration Assay

Journal: Pharmaceutics

Article Title: Investigations on Alkanediols as Alternative Preservatives in a Nonionic Hydrophilic Cream

doi: 10.3390/pharmaceutics12111117

Figure Lengend Snippet: SAXS diffraction patterns of mixed crystals of (i) cetostearyl alcohol, polysorbate 60 and water in the presence of (ii) 2-methyl-2,4-pentanediol, (iii) 1,2-pentanediol, (iv) 1,2-hexanediol, (v) 1,2-octanediol.

Article Snippet: 1,2-Pentanediol, 2-methyl-2,4-pentanediol, and 1,2-hexanediol (Sigma-Aldrich Chemie GmbH, Taufkirchen, Germany), polysorbate 60 (Kolliphor PS 60, BASF SE, Ludwigshafen, Germany), cetostearyl alcohol (Kolliwax CSA, BASF SE, Ludwigshafen, Germany), glycerol 85% (Dr. Willmar Schwabe GmbH & Co. KG, Karlsruhe, Germany), white soft paraffin (Sasol Performance Chemicals, Hamburg, Germany), potassium sorbate (Caesar & Loretz GmbH, Hilden, Germany), citric acid (Jungbunzlauer Suisse AG, Basel, Switzerland).

Techniques:

Journal: Pharmaceutics

Article Title: Investigations on Alkanediols as Alternative Preservatives in a Nonionic Hydrophilic Cream

doi: 10.3390/pharmaceutics12111117

Figure Lengend Snippet: Lamellar distances of mixed crystals of cetostearyl alcohol, polysorbate 60, water and in the presence of different alkanediols.

Article Snippet: 1,2-Pentanediol, 2-methyl-2,4-pentanediol, and 1,2-hexanediol (Sigma-Aldrich Chemie GmbH, Taufkirchen, Germany), polysorbate 60 (Kolliphor PS 60, BASF SE, Ludwigshafen, Germany), cetostearyl alcohol (Kolliwax CSA, BASF SE, Ludwigshafen, Germany), glycerol 85% (Dr. Willmar Schwabe GmbH & Co. KG, Karlsruhe, Germany), white soft paraffin (Sasol Performance Chemicals, Hamburg, Germany), potassium sorbate (Caesar & Loretz GmbH, Hilden, Germany), citric acid (Jungbunzlauer Suisse AG, Basel, Switzerland).

Techniques: